Previous work has suggested that an interaction between local selective (e.g., glutamatergic) excitation and global gain modulation (via norepinephrine) amplifies selectivity in information processing. Mather et al. extend this existing theory by suggesting that localized gain modulation may further mediate this effect – an interesting prospect that invites new theoretical and experimental work.
This page contains links to original data from experiments run at the Princeton Neuroscience Institute. These data are available to others for educational purposes. If they are used in publications, please cite the source of the data by indicating the published reference and the address of this website